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ASIC1a affects hypothalamic signaling and regulates the daily rhythm of body temperature in mice

The body temperature of mice is higher at night than during the day. We show here that global deletion of acid-sensing ion channel 1a (ASIC1a) results in lower body temperature during a part of the night. ASICs are pH sensors that modulate neuronal activity. The deletion of ASIC1a decreased the volu...

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Detalles Bibliográficos
Autores principales:	Peng, Zhong, Ziros, Panos G., Martini, Tomaz, Liao, Xiao-Hui, Stoop, Ron, Refetoff, Samuel, Albrecht, Urs, Sykiotis, Gerasimos P., Kellenberger, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435469/ https://www.ncbi.nlm.nih.gov/pubmed/37591947 http://dx.doi.org/10.1038/s42003-023-05221-2

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