Molecular modelling and site-directed mutagenesis provide insight into saccharide pyruvylation by the Paenibacillus alvei CsaB enzyme

Pyruvylation is a biologically versatile but mechanistically unexplored saccharide modification. 4,6-Ketal pyruvylated N-acetylmannosamine within bacterial secondary cell wall polymers serves as a cell wall anchoring epitope for proteins possessing a terminal S-layer homology domain trimer. The pyru...

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Detalles Bibliográficos
Autores principales: Stefanović, Cordula, Hager-Mair, Fiona F., Breslmayr, Erik, López-Guzmán, Arturo, Lim, Charlie, Blaukopf, Markus, Kosma, Paul, Oostenbrink, Chris, Ludwig, Roland, Schäffer, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435577/
https://www.ncbi.nlm.nih.gov/pubmed/37591902
http://dx.doi.org/10.1038/s41598-023-40072-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435577/
https://www.ncbi.nlm.nih.gov/pubmed/37591902
http://dx.doi.org/10.1038/s41598-023-40072-1

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