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Molecular modelling and site-directed mutagenesis provide insight into saccharide pyruvylation by the Paenibacillus alvei CsaB enzyme
Pyruvylation is a biologically versatile but mechanistically unexplored saccharide modification. 4,6-Ketal pyruvylated N-acetylmannosamine within bacterial secondary cell wall polymers serves as a cell wall anchoring epitope for proteins possessing a terminal S-layer homology domain trimer. The pyru...
Autores principales: | Stefanović, Cordula, Hager-Mair, Fiona F., Breslmayr, Erik, López-Guzmán, Arturo, Lim, Charlie, Blaukopf, Markus, Kosma, Paul, Oostenbrink, Chris, Ludwig, Roland, Schäffer, Christina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435577/ https://www.ncbi.nlm.nih.gov/pubmed/37591902 http://dx.doi.org/10.1038/s41598-023-40072-1 |
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