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Chromoendoscopy in Combination with Random Biopsies for Patients with Pathogenic CDH1 Mutations Undergoing Endoscopic Surveillance
OBJECTIVES: Germline mutations in the CDH1-gene are identified as the cause of 30–40% of cases of hereditary diffuse gastric cancer, an autosomal-dominant inherited cancer predisposition syndrome. Given this high risk of developing diffuse gastric cancer, carriers of a pathogenic CDH1 germline mutat...
Autores principales: | Ruf, Benjamin, Roggia, Cristiana, Schroeder, Christopher, Mattern, Sven, Fend, Falko, Klag, Thomas, Götz, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435617/ https://www.ncbi.nlm.nih.gov/pubmed/35499650 http://dx.doi.org/10.1007/s12029-022-00831-1 |
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