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Severe maternal morbidity following stillbirth in Western Australia 2000–2015: a population-based study
PURPOSE: There is scant literature about the management of stillbirth and the subsequent risk of severe maternal morbidity (SMM). We aimed to assess the risk of SMM associated with stillbirths compared with live births and whether this differed by the presence of maternal comorbidities. METHODS: In...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435652/ https://www.ncbi.nlm.nih.gov/pubmed/36109376 http://dx.doi.org/10.1007/s00404-022-06782-z |
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author | Bailey, Helen D. Adane, Akilew A. White, Scott W. Farrant, Brad M. Shepherd, Carrington C. J. |
author_facet | Bailey, Helen D. Adane, Akilew A. White, Scott W. Farrant, Brad M. Shepherd, Carrington C. J. |
author_sort | Bailey, Helen D. |
collection | PubMed |
description | PURPOSE: There is scant literature about the management of stillbirth and the subsequent risk of severe maternal morbidity (SMM). We aimed to assess the risk of SMM associated with stillbirths compared with live births and whether this differed by the presence of maternal comorbidities. METHODS: In this retrospective cohort study, we used a population-based dataset of all stillbirths and live births ≥ 20 weeks’ gestation in Western Australia between 2000 and 2015. SMM was identified using a published Australian composite for use with routinely collected hospital morbidity data. Maternal comorbidities were identified in the Hospital Morbidity Data Collection or the Midwives Notification System using a modified Australian chronic disease composite. Multivariable Poisson regression was used to estimate relative risks (RRs) and 95% confidence intervals (CIs) for factors associated with SMM in analyses stratified by the presence of maternal comorbidities. Singleton and multiple pregnancies were examined separately. RESULTS: This study included 458,639 singleton births (2319 stillbirths and 456,320 live births). The adjusted RRs for SMM among stillbirths were 2.30 (95% CI 1.77, 3.00) for those without comorbidities and 4.80 (95% CI 4.11, 5.59) (Interaction P value < 0.0001) for those with comorbidities compared to live births without and with comorbidities, respectively. CONCLUSION: In Western Australia between 2000 and 2015, mothers of stillbirths both with and without any maternal comorbidities had an increased risk of SMM compared with live births. Further investigation into why women who have had a stillbirth without any existing conditions or pregnancy complications develop SMM is warranted. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00404-022-06782-z. |
format | Online Article Text |
id | pubmed-10435652 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-104356522023-08-19 Severe maternal morbidity following stillbirth in Western Australia 2000–2015: a population-based study Bailey, Helen D. Adane, Akilew A. White, Scott W. Farrant, Brad M. Shepherd, Carrington C. J. Arch Gynecol Obstet Maternal-Fetal Medicine PURPOSE: There is scant literature about the management of stillbirth and the subsequent risk of severe maternal morbidity (SMM). We aimed to assess the risk of SMM associated with stillbirths compared with live births and whether this differed by the presence of maternal comorbidities. METHODS: In this retrospective cohort study, we used a population-based dataset of all stillbirths and live births ≥ 20 weeks’ gestation in Western Australia between 2000 and 2015. SMM was identified using a published Australian composite for use with routinely collected hospital morbidity data. Maternal comorbidities were identified in the Hospital Morbidity Data Collection or the Midwives Notification System using a modified Australian chronic disease composite. Multivariable Poisson regression was used to estimate relative risks (RRs) and 95% confidence intervals (CIs) for factors associated with SMM in analyses stratified by the presence of maternal comorbidities. Singleton and multiple pregnancies were examined separately. RESULTS: This study included 458,639 singleton births (2319 stillbirths and 456,320 live births). The adjusted RRs for SMM among stillbirths were 2.30 (95% CI 1.77, 3.00) for those without comorbidities and 4.80 (95% CI 4.11, 5.59) (Interaction P value < 0.0001) for those with comorbidities compared to live births without and with comorbidities, respectively. CONCLUSION: In Western Australia between 2000 and 2015, mothers of stillbirths both with and without any maternal comorbidities had an increased risk of SMM compared with live births. Further investigation into why women who have had a stillbirth without any existing conditions or pregnancy complications develop SMM is warranted. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00404-022-06782-z. Springer Berlin Heidelberg 2022-09-15 2023 /pmc/articles/PMC10435652/ /pubmed/36109376 http://dx.doi.org/10.1007/s00404-022-06782-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Maternal-Fetal Medicine Bailey, Helen D. Adane, Akilew A. White, Scott W. Farrant, Brad M. Shepherd, Carrington C. J. Severe maternal morbidity following stillbirth in Western Australia 2000–2015: a population-based study |
title | Severe maternal morbidity following stillbirth in Western Australia 2000–2015: a population-based study |
title_full | Severe maternal morbidity following stillbirth in Western Australia 2000–2015: a population-based study |
title_fullStr | Severe maternal morbidity following stillbirth in Western Australia 2000–2015: a population-based study |
title_full_unstemmed | Severe maternal morbidity following stillbirth in Western Australia 2000–2015: a population-based study |
title_short | Severe maternal morbidity following stillbirth in Western Australia 2000–2015: a population-based study |
title_sort | severe maternal morbidity following stillbirth in western australia 2000–2015: a population-based study |
topic | Maternal-Fetal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435652/ https://www.ncbi.nlm.nih.gov/pubmed/36109376 http://dx.doi.org/10.1007/s00404-022-06782-z |
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