TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away

Tripartite motif-containing protein 21 (TRIM21) is a cytosolic antibody receptor and E3 ubiquitin ligase that promotes destruction of a broad range of pathogens. TRIM21 also underlies the antibody-dependent protein targeting method Trim-Away. Current evidence suggests that TRIM21 binding to antibodi...

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Detalles Bibliográficos
Autores principales: Mevissen, Tycho E.T., Prasad, Anisa V., Walter, Johannes C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435667/
https://www.ncbi.nlm.nih.gov/pubmed/36807144
http://dx.doi.org/10.1016/j.celrep.2023.112125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435667/
https://www.ncbi.nlm.nih.gov/pubmed/36807144
http://dx.doi.org/10.1016/j.celrep.2023.112125

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