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TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away
Tripartite motif-containing protein 21 (TRIM21) is a cytosolic antibody receptor and E3 ubiquitin ligase that promotes destruction of a broad range of pathogens. TRIM21 also underlies the antibody-dependent protein targeting method Trim-Away. Current evidence suggests that TRIM21 binding to antibodi...
Autores principales: | Mevissen, Tycho E.T., Prasad, Anisa V., Walter, Johannes C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435667/ https://www.ncbi.nlm.nih.gov/pubmed/36807144 http://dx.doi.org/10.1016/j.celrep.2023.112125 |
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