Advances in management of primary myelofibrosis and polycythaemia vera: Implications in clinical practice

Primary myelofibrosis (PMF) and polycythaemia vera (PV) are rare BCR‐ABL1‐negative myeloproliferative neoplasms, associated with an increased risk of thrombosis, haemorrhagic complications and progression to fibrosis or leukaemia or fibrosis for PV. Both diseases are characterised by biological and...

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Autores principales: Amé, Shanti, Barraco, Fiorenza, Ianotto, Jean‐Christophe, Jourdan, Eric, Rey, Jérôme, Viallard, Jean‐François, Wémeau, Mathieu, Kiladjian, Jean‐Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435696/
https://www.ncbi.nlm.nih.gov/pubmed/37601853
http://dx.doi.org/10.1002/jha2.734
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author Amé, Shanti
Barraco, Fiorenza
Ianotto, Jean‐Christophe
Jourdan, Eric
Rey, Jérôme
Viallard, Jean‐François
Wémeau, Mathieu
Kiladjian, Jean‐Jacques
author_facet Amé, Shanti
Barraco, Fiorenza
Ianotto, Jean‐Christophe
Jourdan, Eric
Rey, Jérôme
Viallard, Jean‐François
Wémeau, Mathieu
Kiladjian, Jean‐Jacques
author_sort Amé, Shanti
collection PubMed
description Primary myelofibrosis (PMF) and polycythaemia vera (PV) are rare BCR‐ABL1‐negative myeloproliferative neoplasms, associated with an increased risk of thrombosis, haemorrhagic complications and progression to fibrosis or leukaemia or fibrosis for PV. Both diseases are characterised by biological and clinical heterogeneity, leading to great variability in their management in routine clinical practice. In this review, we present an updated overview of the diagnosis, prognosis and treatment of PMF and PV, and we discuss how our multidisciplinary expert group based across France translates this evidence‐based knowledge into routine clinical practice.
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spelling pubmed-104356962023-08-19 Advances in management of primary myelofibrosis and polycythaemia vera: Implications in clinical practice Amé, Shanti Barraco, Fiorenza Ianotto, Jean‐Christophe Jourdan, Eric Rey, Jérôme Viallard, Jean‐François Wémeau, Mathieu Kiladjian, Jean‐Jacques EJHaem Reviews Primary myelofibrosis (PMF) and polycythaemia vera (PV) are rare BCR‐ABL1‐negative myeloproliferative neoplasms, associated with an increased risk of thrombosis, haemorrhagic complications and progression to fibrosis or leukaemia or fibrosis for PV. Both diseases are characterised by biological and clinical heterogeneity, leading to great variability in their management in routine clinical practice. In this review, we present an updated overview of the diagnosis, prognosis and treatment of PMF and PV, and we discuss how our multidisciplinary expert group based across France translates this evidence‐based knowledge into routine clinical practice. John Wiley and Sons Inc. 2023-06-07 /pmc/articles/PMC10435696/ /pubmed/37601853 http://dx.doi.org/10.1002/jha2.734 Text en © 2023 The Authors. eJHaem published by British Society for Haematology and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Amé, Shanti
Barraco, Fiorenza
Ianotto, Jean‐Christophe
Jourdan, Eric
Rey, Jérôme
Viallard, Jean‐François
Wémeau, Mathieu
Kiladjian, Jean‐Jacques
Advances in management of primary myelofibrosis and polycythaemia vera: Implications in clinical practice
title Advances in management of primary myelofibrosis and polycythaemia vera: Implications in clinical practice
title_full Advances in management of primary myelofibrosis and polycythaemia vera: Implications in clinical practice
title_fullStr Advances in management of primary myelofibrosis and polycythaemia vera: Implications in clinical practice
title_full_unstemmed Advances in management of primary myelofibrosis and polycythaemia vera: Implications in clinical practice
title_short Advances in management of primary myelofibrosis and polycythaemia vera: Implications in clinical practice
title_sort advances in management of primary myelofibrosis and polycythaemia vera: implications in clinical practice
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435696/
https://www.ncbi.nlm.nih.gov/pubmed/37601853
http://dx.doi.org/10.1002/jha2.734
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