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Leukaemic cells expressing ETV6::FRK are sensitive to dasatinib in vivo

ETV6::Fyn‐related kinase (FRK), which is a Src family tyrosine‐kinase‐related fusion gene and firstly identified in our patient with paediatric high risk B cell precursor acute lymphoblastic leukaemia (B‐ALL), has no evidence of efficacy of tyrosine kinase inhibitor in vivo. We performed functional...

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Detalles Bibliográficos
Autores principales: Mayumi, Azusa, Imamura, Toshihiko, Yoshida, Hideki, Osone, Shinya, Yasuda, Takahiko, Iehara, Tomoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435712/
https://www.ncbi.nlm.nih.gov/pubmed/37601849
http://dx.doi.org/10.1002/jha2.701