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Neuroblastoma of the lumbosacral canal in an adult: a case report and literature review

Neuroblastoma (NB) is a leading cause of death in children. It usually occurs in the adrenal gland and rarely in the spinal canal. Here, we report the case of a 48-year-old male patient with abnormal thickening of the cauda equina nerve as revealed by lumbosacral magnetic resonance imaging. The pati...

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Autores principales: Jiang, Qingyu, Gao, Haihao, Gao, Gan, Li, Yang, Cheng, Haofeng, Shi, Guoliang, Shang, Aijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435846/
https://www.ncbi.nlm.nih.gov/pubmed/37602246
http://dx.doi.org/10.3389/fneur.2023.1195664
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author Jiang, Qingyu
Gao, Haihao
Gao, Gan
Li, Yang
Cheng, Haofeng
Shi, Guoliang
Shang, Aijia
author_facet Jiang, Qingyu
Gao, Haihao
Gao, Gan
Li, Yang
Cheng, Haofeng
Shi, Guoliang
Shang, Aijia
author_sort Jiang, Qingyu
collection PubMed
description Neuroblastoma (NB) is a leading cause of death in children. It usually occurs in the adrenal gland and rarely in the spinal canal. Here, we report the case of a 48-year-old male patient with abnormal thickening of the cauda equina nerve as revealed by lumbosacral magnetic resonance imaging. The patient’s main clinical manifestations were numbness and pain in both lower limbs. The patient underwent surgical treatment; however, intraoperatively, an unclear border was observed between the cauda equina nerve and the tumor; therefore, the tumor was not forcibly excised. The postoperative pathological results were reported as NB. The disease known as NB, which is extremely rare. We believe that a pathological biopsy is extremely vital for diagnosing NB, and aggressive post-operative radio-chemotherapy could potentially prolong the patient’s survival time.
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spelling pubmed-104358462023-08-19 Neuroblastoma of the lumbosacral canal in an adult: a case report and literature review Jiang, Qingyu Gao, Haihao Gao, Gan Li, Yang Cheng, Haofeng Shi, Guoliang Shang, Aijia Front Neurol Neurology Neuroblastoma (NB) is a leading cause of death in children. It usually occurs in the adrenal gland and rarely in the spinal canal. Here, we report the case of a 48-year-old male patient with abnormal thickening of the cauda equina nerve as revealed by lumbosacral magnetic resonance imaging. The patient’s main clinical manifestations were numbness and pain in both lower limbs. The patient underwent surgical treatment; however, intraoperatively, an unclear border was observed between the cauda equina nerve and the tumor; therefore, the tumor was not forcibly excised. The postoperative pathological results were reported as NB. The disease known as NB, which is extremely rare. We believe that a pathological biopsy is extremely vital for diagnosing NB, and aggressive post-operative radio-chemotherapy could potentially prolong the patient’s survival time. Frontiers Media S.A. 2023-08-03 /pmc/articles/PMC10435846/ /pubmed/37602246 http://dx.doi.org/10.3389/fneur.2023.1195664 Text en Copyright © 2023 Jiang, Gao, Gao, Li, Cheng, Shi and Shang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Jiang, Qingyu
Gao, Haihao
Gao, Gan
Li, Yang
Cheng, Haofeng
Shi, Guoliang
Shang, Aijia
Neuroblastoma of the lumbosacral canal in an adult: a case report and literature review
title Neuroblastoma of the lumbosacral canal in an adult: a case report and literature review
title_full Neuroblastoma of the lumbosacral canal in an adult: a case report and literature review
title_fullStr Neuroblastoma of the lumbosacral canal in an adult: a case report and literature review
title_full_unstemmed Neuroblastoma of the lumbosacral canal in an adult: a case report and literature review
title_short Neuroblastoma of the lumbosacral canal in an adult: a case report and literature review
title_sort neuroblastoma of the lumbosacral canal in an adult: a case report and literature review
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435846/
https://www.ncbi.nlm.nih.gov/pubmed/37602246
http://dx.doi.org/10.3389/fneur.2023.1195664
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