Development of an immunoassay for the simultaneous detection of GADA and ZnT8A in autoimmune diabetes using a ZnT8/GAD65 chimeric molecule

INTRODUCTION: The combined presence of autoantibodies to the 65 kDa isoform of glutamic acid decarboxylase (GADA) and to the islet-specific cation efflux transporter ZnT8 (ZnT8A) in serum is the best predictive sign of the loss of immune tolerance and the clinical manifestation of autoimmune diabete...

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Detalles Bibliográficos
Autores principales: Trabucchi, Aldana, Bombicino, Silvina Sonia, Sabljic, Adriana Victoria, Marfía, Juan Ignacio, Targovnik, Alexandra Marisa, Iacono, Rubén Francisco, Miranda, María Victoria, Valdez, Silvina Noemí
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435855/
https://www.ncbi.nlm.nih.gov/pubmed/37600804
http://dx.doi.org/10.3389/fimmu.2023.1219857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435855/
https://www.ncbi.nlm.nih.gov/pubmed/37600804
http://dx.doi.org/10.3389/fimmu.2023.1219857

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