Metformin is a metabolic modulator and radiosensitiser in rectal cancer

Resistance to neoadjuvant chemoradiation therapy, is a major challenge in the management of rectal cancer. Increasing evidence supports a role for altered energy metabolism in the resistance of tumours to anti-cancer therapy, suggesting that targeting tumour metabolism may have potential as a novel...

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Detalles Bibliográficos
Autores principales: Buckley, Croí E., O’Brien, Rebecca M., Nugent, Timothy S., Donlon, Noel E., O’Connell, Fiona, Reynolds, John V., Hafeez, Adnan, O’Ríordáin, Diarmuid S., Hannon, Robert A., Neary, Paul, Kalbassi, Reza, Mehigan, Brian J., McCormick, Paul H., Dunne, Cara, Kelly, Michael E., Larkin, John O., O’Sullivan, Jacintha, Lynam-Lennon, Niamh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435980/
https://www.ncbi.nlm.nih.gov/pubmed/37601689
http://dx.doi.org/10.3389/fonc.2023.1216911

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