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In vitro and in vivo efficacy of Molnupiravir against Zika virus infections
• Molnupiravir exhibits effective antiviral activity against ZIKV in vitro. • Intraperitoneal administration of Molnupiravir protects mice from lethal ZIKV challenge. • Molnupiravir might act on the replication phase of the ZIKV life cycle.
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wuhan Institute of Virology, Chinese Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436044/ https://www.ncbi.nlm.nih.gov/pubmed/37268161 http://dx.doi.org/10.1016/j.virs.2023.05.011 |
| _version_ | 1785092241223581696 |
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| author | Wang, Zhuang Yang, Shaokang Dai, Qingsong Guo, Xiaojia Li, Yuexiang Li, Wei Yang, Xiaotong Yang, Jingjing Yan, Xintong Tao, Huimin Luo, Chongda Li, Song Chen, Xingjuan Cao, Ruiyuan Zhong, Wu |
| author_facet | Wang, Zhuang Yang, Shaokang Dai, Qingsong Guo, Xiaojia Li, Yuexiang Li, Wei Yang, Xiaotong Yang, Jingjing Yan, Xintong Tao, Huimin Luo, Chongda Li, Song Chen, Xingjuan Cao, Ruiyuan Zhong, Wu |
| author_sort | Wang, Zhuang |
| collection | PubMed |
| description | • Molnupiravir exhibits effective antiviral activity against ZIKV in vitro. • Intraperitoneal administration of Molnupiravir protects mice from lethal ZIKV challenge. • Molnupiravir might act on the replication phase of the ZIKV life cycle. |
| format | Online Article Text |
| id | pubmed-10436044 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | Wuhan Institute of Virology, Chinese Academy of Sciences |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-104360442023-08-19 In vitro and in vivo efficacy of Molnupiravir against Zika virus infections Wang, Zhuang Yang, Shaokang Dai, Qingsong Guo, Xiaojia Li, Yuexiang Li, Wei Yang, Xiaotong Yang, Jingjing Yan, Xintong Tao, Huimin Luo, Chongda Li, Song Chen, Xingjuan Cao, Ruiyuan Zhong, Wu Virol Sin Letter • Molnupiravir exhibits effective antiviral activity against ZIKV in vitro. • Intraperitoneal administration of Molnupiravir protects mice from lethal ZIKV challenge. • Molnupiravir might act on the replication phase of the ZIKV life cycle. Wuhan Institute of Virology, Chinese Academy of Sciences 2023-06-01 /pmc/articles/PMC10436044/ /pubmed/37268161 http://dx.doi.org/10.1016/j.virs.2023.05.011 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Letter Wang, Zhuang Yang, Shaokang Dai, Qingsong Guo, Xiaojia Li, Yuexiang Li, Wei Yang, Xiaotong Yang, Jingjing Yan, Xintong Tao, Huimin Luo, Chongda Li, Song Chen, Xingjuan Cao, Ruiyuan Zhong, Wu In vitro and in vivo efficacy of Molnupiravir against Zika virus infections |
| title | In vitro and in vivo efficacy of Molnupiravir against Zika virus infections |
| title_full | In vitro and in vivo efficacy of Molnupiravir against Zika virus infections |
| title_fullStr | In vitro and in vivo efficacy of Molnupiravir against Zika virus infections |
| title_full_unstemmed | In vitro and in vivo efficacy of Molnupiravir against Zika virus infections |
| title_short | In vitro and in vivo efficacy of Molnupiravir against Zika virus infections |
| title_sort | in vitro and in vivo efficacy of molnupiravir against zika virus infections |
| topic | Letter |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436044/ https://www.ncbi.nlm.nih.gov/pubmed/37268161 http://dx.doi.org/10.1016/j.virs.2023.05.011 |
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