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Monoclonal antibodies binding to different epitopes of CD20 differentially sensitize DLBCL to different classes of chemotherapy

INTRODUCTION: Rituximab (R), an anti-CD20 monoclonal antibody (mAb) and the world’s first approved antibody for oncology patients, was combined with the CHOP chemotherapy regimen and markedly improved the prognosis of all B- cell–derived lymphomas, the most common hematological malignancy worldwide....

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Detalles Bibliográficos
Autores principales: Lee, Brian, Pierpont, Tim, August, Avery, Richards, Kristy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436104/
https://www.ncbi.nlm.nih.gov/pubmed/37601699
http://dx.doi.org/10.3389/fonc.2023.1159484