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The value of surgery in the treatment of gestational choriocarcinoma: A case report

INTRODUCTION AND IMPORTANCE: Gestational choriocarcinoma is a rare malignant trophoblastic tumor; it is characterized by its high metastatic potential and chemosensitivity. Hysterectomy also has a role in the management of this tumor. CASE PRESENTATION: We report a rare case of gestational choriocar...

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Detalles Bibliográficos
Autores principales: Bencherifi, Younes, Abbassi, Imane El, Karoini, Douha El, Ennachit, Mohammed, Benhessou, Mustapha, Kerroumi, Mohammed El
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436163/
https://www.ncbi.nlm.nih.gov/pubmed/37591194
http://dx.doi.org/10.1016/j.ijscr.2023.108634
Descripción
Sumario:INTRODUCTION AND IMPORTANCE: Gestational choriocarcinoma is a rare malignant trophoblastic tumor; it is characterized by its high metastatic potential and chemosensitivity. Hysterectomy also has a role in the management of this tumor. CASE PRESENTATION: We report a rare case of gestational choriocarcinoma in a young woman initially classified as low risk (FIGO2), treated by surgery after chemoresistance to different chemotherapy protocols, marked by an excellent clinical and biochemical improvement. CLINICAL DISCUSSION: Gestational choriocarcinoma is a malignant tumor of the villous trophoblast, devoid of placental villi and vesicles.Despite the excellence of chemotherapy, surgery has a significant place in the treatment of gestational trophoblastic tumors. The most common modality of surgical treatment is total hysterectomy. Ovarian metastases are rare; the ovaries may be preserved depending on the age of the patients. CONCLUSION: The progress of recent years lies in the clarification of the therapeutic strategies used in the treatment of gestational trophoblastic tumors, in particular choriocarcinoma.