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The value of surgery in the treatment of gestational choriocarcinoma: A case report
INTRODUCTION AND IMPORTANCE: Gestational choriocarcinoma is a rare malignant trophoblastic tumor; it is characterized by its high metastatic potential and chemosensitivity. Hysterectomy also has a role in the management of this tumor. CASE PRESENTATION: We report a rare case of gestational choriocar...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436163/ https://www.ncbi.nlm.nih.gov/pubmed/37591194 http://dx.doi.org/10.1016/j.ijscr.2023.108634 |
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author | Bencherifi, Younes Abbassi, Imane El Karoini, Douha El Ennachit, Mohammed Benhessou, Mustapha Kerroumi, Mohammed El |
author_facet | Bencherifi, Younes Abbassi, Imane El Karoini, Douha El Ennachit, Mohammed Benhessou, Mustapha Kerroumi, Mohammed El |
author_sort | Bencherifi, Younes |
collection | PubMed |
description | INTRODUCTION AND IMPORTANCE: Gestational choriocarcinoma is a rare malignant trophoblastic tumor; it is characterized by its high metastatic potential and chemosensitivity. Hysterectomy also has a role in the management of this tumor. CASE PRESENTATION: We report a rare case of gestational choriocarcinoma in a young woman initially classified as low risk (FIGO2), treated by surgery after chemoresistance to different chemotherapy protocols, marked by an excellent clinical and biochemical improvement. CLINICAL DISCUSSION: Gestational choriocarcinoma is a malignant tumor of the villous trophoblast, devoid of placental villi and vesicles.Despite the excellence of chemotherapy, surgery has a significant place in the treatment of gestational trophoblastic tumors. The most common modality of surgical treatment is total hysterectomy. Ovarian metastases are rare; the ovaries may be preserved depending on the age of the patients. CONCLUSION: The progress of recent years lies in the clarification of the therapeutic strategies used in the treatment of gestational trophoblastic tumors, in particular choriocarcinoma. |
format | Online Article Text |
id | pubmed-10436163 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-104361632023-08-19 The value of surgery in the treatment of gestational choriocarcinoma: A case report Bencherifi, Younes Abbassi, Imane El Karoini, Douha El Ennachit, Mohammed Benhessou, Mustapha Kerroumi, Mohammed El Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Gestational choriocarcinoma is a rare malignant trophoblastic tumor; it is characterized by its high metastatic potential and chemosensitivity. Hysterectomy also has a role in the management of this tumor. CASE PRESENTATION: We report a rare case of gestational choriocarcinoma in a young woman initially classified as low risk (FIGO2), treated by surgery after chemoresistance to different chemotherapy protocols, marked by an excellent clinical and biochemical improvement. CLINICAL DISCUSSION: Gestational choriocarcinoma is a malignant tumor of the villous trophoblast, devoid of placental villi and vesicles.Despite the excellence of chemotherapy, surgery has a significant place in the treatment of gestational trophoblastic tumors. The most common modality of surgical treatment is total hysterectomy. Ovarian metastases are rare; the ovaries may be preserved depending on the age of the patients. CONCLUSION: The progress of recent years lies in the clarification of the therapeutic strategies used in the treatment of gestational trophoblastic tumors, in particular choriocarcinoma. Elsevier 2023-08-12 /pmc/articles/PMC10436163/ /pubmed/37591194 http://dx.doi.org/10.1016/j.ijscr.2023.108634 Text en © 2023 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Bencherifi, Younes Abbassi, Imane El Karoini, Douha El Ennachit, Mohammed Benhessou, Mustapha Kerroumi, Mohammed El The value of surgery in the treatment of gestational choriocarcinoma: A case report |
title | The value of surgery in the treatment of gestational choriocarcinoma: A case report |
title_full | The value of surgery in the treatment of gestational choriocarcinoma: A case report |
title_fullStr | The value of surgery in the treatment of gestational choriocarcinoma: A case report |
title_full_unstemmed | The value of surgery in the treatment of gestational choriocarcinoma: A case report |
title_short | The value of surgery in the treatment of gestational choriocarcinoma: A case report |
title_sort | value of surgery in the treatment of gestational choriocarcinoma: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436163/ https://www.ncbi.nlm.nih.gov/pubmed/37591194 http://dx.doi.org/10.1016/j.ijscr.2023.108634 |
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