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The value of surgery in the treatment of gestational choriocarcinoma: A case report

INTRODUCTION AND IMPORTANCE: Gestational choriocarcinoma is a rare malignant trophoblastic tumor; it is characterized by its high metastatic potential and chemosensitivity. Hysterectomy also has a role in the management of this tumor. CASE PRESENTATION: We report a rare case of gestational choriocar...

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Autores principales: Bencherifi, Younes, Abbassi, Imane El, Karoini, Douha El, Ennachit, Mohammed, Benhessou, Mustapha, Kerroumi, Mohammed El
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436163/
https://www.ncbi.nlm.nih.gov/pubmed/37591194
http://dx.doi.org/10.1016/j.ijscr.2023.108634
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author Bencherifi, Younes
Abbassi, Imane El
Karoini, Douha El
Ennachit, Mohammed
Benhessou, Mustapha
Kerroumi, Mohammed El
author_facet Bencherifi, Younes
Abbassi, Imane El
Karoini, Douha El
Ennachit, Mohammed
Benhessou, Mustapha
Kerroumi, Mohammed El
author_sort Bencherifi, Younes
collection PubMed
description INTRODUCTION AND IMPORTANCE: Gestational choriocarcinoma is a rare malignant trophoblastic tumor; it is characterized by its high metastatic potential and chemosensitivity. Hysterectomy also has a role in the management of this tumor. CASE PRESENTATION: We report a rare case of gestational choriocarcinoma in a young woman initially classified as low risk (FIGO2), treated by surgery after chemoresistance to different chemotherapy protocols, marked by an excellent clinical and biochemical improvement. CLINICAL DISCUSSION: Gestational choriocarcinoma is a malignant tumor of the villous trophoblast, devoid of placental villi and vesicles.Despite the excellence of chemotherapy, surgery has a significant place in the treatment of gestational trophoblastic tumors. The most common modality of surgical treatment is total hysterectomy. Ovarian metastases are rare; the ovaries may be preserved depending on the age of the patients. CONCLUSION: The progress of recent years lies in the clarification of the therapeutic strategies used in the treatment of gestational trophoblastic tumors, in particular choriocarcinoma.
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spelling pubmed-104361632023-08-19 The value of surgery in the treatment of gestational choriocarcinoma: A case report Bencherifi, Younes Abbassi, Imane El Karoini, Douha El Ennachit, Mohammed Benhessou, Mustapha Kerroumi, Mohammed El Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Gestational choriocarcinoma is a rare malignant trophoblastic tumor; it is characterized by its high metastatic potential and chemosensitivity. Hysterectomy also has a role in the management of this tumor. CASE PRESENTATION: We report a rare case of gestational choriocarcinoma in a young woman initially classified as low risk (FIGO2), treated by surgery after chemoresistance to different chemotherapy protocols, marked by an excellent clinical and biochemical improvement. CLINICAL DISCUSSION: Gestational choriocarcinoma is a malignant tumor of the villous trophoblast, devoid of placental villi and vesicles.Despite the excellence of chemotherapy, surgery has a significant place in the treatment of gestational trophoblastic tumors. The most common modality of surgical treatment is total hysterectomy. Ovarian metastases are rare; the ovaries may be preserved depending on the age of the patients. CONCLUSION: The progress of recent years lies in the clarification of the therapeutic strategies used in the treatment of gestational trophoblastic tumors, in particular choriocarcinoma. Elsevier 2023-08-12 /pmc/articles/PMC10436163/ /pubmed/37591194 http://dx.doi.org/10.1016/j.ijscr.2023.108634 Text en © 2023 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Bencherifi, Younes
Abbassi, Imane El
Karoini, Douha El
Ennachit, Mohammed
Benhessou, Mustapha
Kerroumi, Mohammed El
The value of surgery in the treatment of gestational choriocarcinoma: A case report
title The value of surgery in the treatment of gestational choriocarcinoma: A case report
title_full The value of surgery in the treatment of gestational choriocarcinoma: A case report
title_fullStr The value of surgery in the treatment of gestational choriocarcinoma: A case report
title_full_unstemmed The value of surgery in the treatment of gestational choriocarcinoma: A case report
title_short The value of surgery in the treatment of gestational choriocarcinoma: A case report
title_sort value of surgery in the treatment of gestational choriocarcinoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436163/
https://www.ncbi.nlm.nih.gov/pubmed/37591194
http://dx.doi.org/10.1016/j.ijscr.2023.108634
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