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Generation of epitope tag knock-in mice with CRISPR-Cas9 to study the function of endogenous proteins
Studying endogenous proteins in mice has provided numerous insights into the physiological and pathological roles of these proteins. However, the availability and specificity of protein-specific antibodies often limit such studies. Here we present a protocol for generating epitope tag knock-in mice...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436228/ https://www.ncbi.nlm.nih.gov/pubmed/37585297 http://dx.doi.org/10.1016/j.xpro.2023.102518 |