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Tryptophan-PNA gc Conjugates Self-Assemble to Form Fibers

[Image: see text] Peptide nucleic acids and their conjugates to peptides can self-assemble and generate complex architectures. In this work, we explored the self-assembly of PNA dimers conjugated to the dipeptide WW. Our studies suggest that the indole ring of tryptophan promotes aggregation of the...

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Detalles Bibliográficos
Autores principales: Mosseri, Andrea, Sancho-Albero, María, Mercurio, Flavia Anna, Leone, Marilisa, De Cola, Luisa, Romanelli, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436247/
https://www.ncbi.nlm.nih.gov/pubmed/37486977
http://dx.doi.org/10.1021/acs.bioconjchem.3c00200