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B cell depletion therapy does not resolve chronic active multiple sclerosis lesions

BACKGROUND: Chronic active lesions (CAL) in multiple sclerosis (MS) have been observed even in patients taking high-efficacy disease-modifying therapy, including B-cell depletion. Given that CAL are a major determinant of clinical progression, including progression independent of relapse activity (P...

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Detalles Bibliográficos
Autores principales:	Maggi, Pietro, Bulcke, Colin Vanden, Pedrini, Edoardo, Bugli, Céline, Sellimi, Amina, Wynen, Maxence, Stölting, Anna, Mullins, William A., Kalaitzidis, Grigorios, Lolli, Valentina, Perrotta, Gaetano, El Sankari, Souraya, Duprez, Thierry, Li, Xu, Calabresi, Peter A., van Pesch, Vincent, Reich, Daniel S., Absinta, Martina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436266/ https://www.ncbi.nlm.nih.gov/pubmed/37437310 http://dx.doi.org/10.1016/j.ebiom.2023.104701

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