Experimental NOE, Chemical Shift, and Proline Isomerization Data Provide Detailed Insights into Amelotin Oligomerization

[Image: see text] Amelotin is an intrinsically disordered protein (IDP) rich in Pro residues and is involved in hydroxyapatite mineralization. It rapidly oligomerizes under physiological conditions of pH and pressure but reverts to its monomeric IDP state at elevated pressure. We identified a 105-re...

Descripción completa

Detalles Bibliográficos
Autores principales: Chiliveri, Sai Chaitanya, Shen, Yang, Baber, James L., Ying, Jinfa, Sagar, Vatsala, Wistow, Graeme, Anfinrud, Philip, Bax, Ad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436275/
https://www.ncbi.nlm.nih.gov/pubmed/37548612
http://dx.doi.org/10.1021/jacs.3c05710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436275/
https://www.ncbi.nlm.nih.gov/pubmed/37548612
http://dx.doi.org/10.1021/jacs.3c05710

Ejemplares similares