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Case report and literature review: fatal cerebral fat embolism following facial autologous fat graft
BACKGROUND: Severe cerebral artery embolism is a rare complication of facial autologous fat injection. However, its incidence has markedly increased with the recent rise in facial cosmetic procedures. CASE PRESENTATION: We report a 31-year-old Chinese woman who presented with unconsciousness 6 h aft...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436317/ https://www.ncbi.nlm.nih.gov/pubmed/37602257 http://dx.doi.org/10.3389/fneur.2023.1180333 |
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author | Cheng, Yawen Yan, Gezhi Li, Chenyang Han, Xiangning Shang, Jing Shang, Suhang Han, Jianfeng Luo, Guogang Liu, Fude |
author_facet | Cheng, Yawen Yan, Gezhi Li, Chenyang Han, Xiangning Shang, Jing Shang, Suhang Han, Jianfeng Luo, Guogang Liu, Fude |
author_sort | Cheng, Yawen |
collection | PubMed |
description | BACKGROUND: Severe cerebral artery embolism is a rare complication of facial autologous fat injection. However, its incidence has markedly increased with the recent rise in facial cosmetic procedures. CASE PRESENTATION: We report a 31-year-old Chinese woman who presented with unconsciousness 6 h after having undergone a facial autologous fat injection. A neurological examination revealed stupor, bilaterally diminished pupillary light reflexes, right-sided central facial palsy, and no reaction to pain stimulation of right limbs. Diffusion-weighted imaging displayed patchy hyperintense lesions in the left frontal, parietal, and temporal lobes. Magnetic resonance angiography demonstrated fat embolism in the left internal carotid artery, anterior cerebral artery, and middle cerebral artery. We immediately performed mechanical thrombectomy under sufficient preoperative preparations but failed to achieve complete recanalization. Pathological examination of the embolus confirmed the presence of adipocytes. Although we actively administered symptomatic and supportive treatments, the patient eventually died due to the progression of cerebral herniation and systemic infection. CONCLUSION: Due to the ineffectiveness of current treatment and the inferior prognosis, fat embolism, a severe complication of autologous fat graft, should draw the attention of both plastic surgeons and neurologists so that actions may be taken for both its prevention and treatment. |
format | Online Article Text |
id | pubmed-10436317 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104363172023-08-19 Case report and literature review: fatal cerebral fat embolism following facial autologous fat graft Cheng, Yawen Yan, Gezhi Li, Chenyang Han, Xiangning Shang, Jing Shang, Suhang Han, Jianfeng Luo, Guogang Liu, Fude Front Neurol Neurology BACKGROUND: Severe cerebral artery embolism is a rare complication of facial autologous fat injection. However, its incidence has markedly increased with the recent rise in facial cosmetic procedures. CASE PRESENTATION: We report a 31-year-old Chinese woman who presented with unconsciousness 6 h after having undergone a facial autologous fat injection. A neurological examination revealed stupor, bilaterally diminished pupillary light reflexes, right-sided central facial palsy, and no reaction to pain stimulation of right limbs. Diffusion-weighted imaging displayed patchy hyperintense lesions in the left frontal, parietal, and temporal lobes. Magnetic resonance angiography demonstrated fat embolism in the left internal carotid artery, anterior cerebral artery, and middle cerebral artery. We immediately performed mechanical thrombectomy under sufficient preoperative preparations but failed to achieve complete recanalization. Pathological examination of the embolus confirmed the presence of adipocytes. Although we actively administered symptomatic and supportive treatments, the patient eventually died due to the progression of cerebral herniation and systemic infection. CONCLUSION: Due to the ineffectiveness of current treatment and the inferior prognosis, fat embolism, a severe complication of autologous fat graft, should draw the attention of both plastic surgeons and neurologists so that actions may be taken for both its prevention and treatment. Frontiers Media S.A. 2023-08-04 /pmc/articles/PMC10436317/ /pubmed/37602257 http://dx.doi.org/10.3389/fneur.2023.1180333 Text en Copyright © 2023 Cheng, Yan, Li, Han, Shang, Shang, Han, Luo and Liu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Cheng, Yawen Yan, Gezhi Li, Chenyang Han, Xiangning Shang, Jing Shang, Suhang Han, Jianfeng Luo, Guogang Liu, Fude Case report and literature review: fatal cerebral fat embolism following facial autologous fat graft |
title | Case report and literature review: fatal cerebral fat embolism following facial autologous fat graft |
title_full | Case report and literature review: fatal cerebral fat embolism following facial autologous fat graft |
title_fullStr | Case report and literature review: fatal cerebral fat embolism following facial autologous fat graft |
title_full_unstemmed | Case report and literature review: fatal cerebral fat embolism following facial autologous fat graft |
title_short | Case report and literature review: fatal cerebral fat embolism following facial autologous fat graft |
title_sort | case report and literature review: fatal cerebral fat embolism following facial autologous fat graft |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436317/ https://www.ncbi.nlm.nih.gov/pubmed/37602257 http://dx.doi.org/10.3389/fneur.2023.1180333 |
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