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Endothelial MICU1 alleviates diabetic cardiomyopathy by attenuating nitrative stress-mediated cardiac microvascular injury

BACKGROUND: Myocardial microvascular injury is the key event in early diabetic heart disease. The injury of myocardial microvascular endothelial cells (CMECs) is the main cause and trigger of myocardial microvascular disease. Mitochondrial calcium homeostasis plays an important role in maintaining t...

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Detalles Bibliográficos
Autores principales: Shi, Xide, Liu, Chao, Chen, Jiangwei, Zhou, Shiqiang, Li, Yajuan, Zhao, Xingcheng, Xing, Jinliang, Xue, Junhui, Liu, Fengzhou, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436431/
https://www.ncbi.nlm.nih.gov/pubmed/37592255
http://dx.doi.org/10.1186/s12933-023-01941-1

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