Cargando…
Endothelial MICU1 alleviates diabetic cardiomyopathy by attenuating nitrative stress-mediated cardiac microvascular injury
BACKGROUND: Myocardial microvascular injury is the key event in early diabetic heart disease. The injury of myocardial microvascular endothelial cells (CMECs) is the main cause and trigger of myocardial microvascular disease. Mitochondrial calcium homeostasis plays an important role in maintaining t...
Autores principales: | Shi, Xide, Liu, Chao, Chen, Jiangwei, Zhou, Shiqiang, Li, Yajuan, Zhao, Xingcheng, Xing, Jinliang, Xue, Junhui, Liu, Fengzhou, Li, Fei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436431/ https://www.ncbi.nlm.nih.gov/pubmed/37592255 http://dx.doi.org/10.1186/s12933-023-01941-1 |
Ejemplares similares
-
Structures reveal gatekeeping of the mitochondrial Ca(2+) uniporter by MICU1-MICU2
por: Wang, Chongyuan, et al.
Publicado: (2020) -
Structure of the MICU1–MICU2 heterodimer provides insights into the gatekeeping threshold shift
por: Park, Jongseo, et al.
Publicado: (2020) -
Melatonin alleviates angiotensin-II-induced cardiac hypertrophy via activating MICU1 pathway
por: Yang, Yi, et al.
Publicado: (2020) -
MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling
por: Plovanich, Molly, et al.
Publicado: (2013) -
Expression and preliminary characterization of human MICU2
por: Li, Dan, et al.
Publicado: (2016)