Selective neuroimmune modulation by type I interferon drives neuropathology and neurologic dysfunction following traumatic brain injury

Accumulating evidence suggests that type I interferon (IFN-I) signaling is a key contributor to immune cell-mediated neuropathology in neurodegenerative diseases. Recently, we demonstrated a robust upregulation of type I interferon-stimulated genes in microglia and astrocytes following experimental...

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Detalles Bibliográficos
Autores principales: Todd, Brittany P., Luo, Zili, Gilkes, Noah, Chimenti, Michael S., Peterson, Zeru, Mix, Madison R., Harty, John T., Nickl-Jockschat, Thomas, Ferguson, Polly J., Bassuk, Alexander G., Newell, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436463/
https://www.ncbi.nlm.nih.gov/pubmed/37596685
http://dx.doi.org/10.1186/s40478-023-01635-5

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