Defining the ferroptotic phenotype of beta cells in type 1 diabetes and its inhibition as a potential antidiabetic strategy

INTRODUCTION: Recently, the involvement of ferroptotic cell death in the reduction of β-cell mass in diabetes has been demonstrated. To elucidate the mechanisms of β-cell ferroptosis and potential antidiabetic effects of the ferroptosis inhibitor ferrostatin-1 (Fer-1) in vivo, a mouse model of type...

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Detalles Bibliográficos
Autores principales: Markelic, Milica, Stancic, Ana, Saksida, Tamara, Grigorov, Ilijana, Micanovic, Dragica, Velickovic, Ksenija, Martinovic, Vesna, Savic, Nevena, Gudelj, Andjelija, Otasevic, Vesna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437050/
https://www.ncbi.nlm.nih.gov/pubmed/37600723
http://dx.doi.org/10.3389/fendo.2023.1227498

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