Pustular Psoriasis in a Patient Treated with Dupilumab for Atopic Dermatitis: A Case Report

Psoriasis and atopic dermatitis are relatively common in clinical practice, but it is rare for the two diseases to co-occur in the same patient. Dupilumab, an anti-IL-4/IL-13 monoclonal antibody, has been approved for treating moderate to severe AD. In addition to its therapeutic effects, dupilumab...

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Autores principales: Liu, Li, Chen, Jie, Tang, Kangheng, Li, Feng, Li, Si, Ding, Xiaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437099/
https://www.ncbi.nlm.nih.gov/pubmed/37601418
http://dx.doi.org/10.2147/CCID.S420904
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author Liu, Li
Chen, Jie
Tang, Kangheng
Li, Feng
Li, Si
Ding, Xiaojie
author_facet Liu, Li
Chen, Jie
Tang, Kangheng
Li, Feng
Li, Si
Ding, Xiaojie
author_sort Liu, Li
collection PubMed
description Psoriasis and atopic dermatitis are relatively common in clinical practice, but it is rare for the two diseases to co-occur in the same patient. Dupilumab, an anti-IL-4/IL-13 monoclonal antibody, has been approved for treating moderate to severe AD. In addition to its therapeutic effects, dupilumab may induce new cutaneous adverse reactions. We report a rare case of pustular psoriasis induced during the treatment of atopic dermatitis with dupilumab. This case demonstrates the need for caution while treating patients with moderate to severe atopic dermatitis and staying vigilant for the emergence of new symptoms, especially with biological agents.
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spelling pubmed-104370992023-08-19 Pustular Psoriasis in a Patient Treated with Dupilumab for Atopic Dermatitis: A Case Report Liu, Li Chen, Jie Tang, Kangheng Li, Feng Li, Si Ding, Xiaojie Clin Cosmet Investig Dermatol Case Report Psoriasis and atopic dermatitis are relatively common in clinical practice, but it is rare for the two diseases to co-occur in the same patient. Dupilumab, an anti-IL-4/IL-13 monoclonal antibody, has been approved for treating moderate to severe AD. In addition to its therapeutic effects, dupilumab may induce new cutaneous adverse reactions. We report a rare case of pustular psoriasis induced during the treatment of atopic dermatitis with dupilumab. This case demonstrates the need for caution while treating patients with moderate to severe atopic dermatitis and staying vigilant for the emergence of new symptoms, especially with biological agents. Dove 2023-08-14 /pmc/articles/PMC10437099/ /pubmed/37601418 http://dx.doi.org/10.2147/CCID.S420904 Text en © 2023 Liu et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Liu, Li
Chen, Jie
Tang, Kangheng
Li, Feng
Li, Si
Ding, Xiaojie
Pustular Psoriasis in a Patient Treated with Dupilumab for Atopic Dermatitis: A Case Report
title Pustular Psoriasis in a Patient Treated with Dupilumab for Atopic Dermatitis: A Case Report
title_full Pustular Psoriasis in a Patient Treated with Dupilumab for Atopic Dermatitis: A Case Report
title_fullStr Pustular Psoriasis in a Patient Treated with Dupilumab for Atopic Dermatitis: A Case Report
title_full_unstemmed Pustular Psoriasis in a Patient Treated with Dupilumab for Atopic Dermatitis: A Case Report
title_short Pustular Psoriasis in a Patient Treated with Dupilumab for Atopic Dermatitis: A Case Report
title_sort pustular psoriasis in a patient treated with dupilumab for atopic dermatitis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437099/
https://www.ncbi.nlm.nih.gov/pubmed/37601418
http://dx.doi.org/10.2147/CCID.S420904
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