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An assessment of the public health surveillance strategy based on molecular testing during three major pandemic waves of COVID-19 in Brazil

A national laboratory-based surveillance system was adapted to monitor the situation of SARS-CoV-2 in Brazil. The objective of the study was to compare the challenges in implementing COVID-19 surveillance strategies based on the Ministry of Health’s (MoH) distribution of RT-PCR tests to different ty...

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Autores principales: Barberia, Lorena G., Boing, Alexandra, Gusmão, João, Miyajima, Fabio, Abud, Adriano, Kemp, Brigina, Zamudio, Marcela, Moraes de Sousa, Tatiane C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437824/
https://www.ncbi.nlm.nih.gov/pubmed/37594920
http://dx.doi.org/10.1371/journal.pgph.0002164
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author Barberia, Lorena G.
Boing, Alexandra
Gusmão, João
Miyajima, Fabio
Abud, Adriano
Kemp, Brigina
Zamudio, Marcela
Moraes de Sousa, Tatiane C.
author_facet Barberia, Lorena G.
Boing, Alexandra
Gusmão, João
Miyajima, Fabio
Abud, Adriano
Kemp, Brigina
Zamudio, Marcela
Moraes de Sousa, Tatiane C.
author_sort Barberia, Lorena G.
collection PubMed
description A national laboratory-based surveillance system was adapted to monitor the situation of SARS-CoV-2 in Brazil. The objective of the study was to compare the challenges in implementing COVID-19 surveillance strategies based on the Ministry of Health’s (MoH) distribution of RT-PCR tests to different types of laboratories. This retrospective study analyzed the MoH’s testing policies and distribution of RT-PCR tests to laboratories during the first, second, and third waves. Recipient laboratories were divided into groups: public health laboratories that belonged to the national network of public health laboratories (Group 1); public laboratories granted authorization during the pandemic (Group 2); and High-Capacity Testing Centers (Group 3). We analyzed the timing and duration of COVID-19 testing policies and the allocation of tests to laboratories by group and wave. Using t-tests, we analyzed the difference in the weekly average of tests distributed to labs by group and using Pearson’s correlation coefficient, analyzed the test distribution according to infection and death rates. Between epiweek 9, 2020, and epiweek 22, 2022, the MoH distributed an average of 263,004 RT-PCR tests per week. The weekly average of tests distributed was highest in the second wave (310,327 tests), followed by the first (218,005 tests) and third waves (201,226 tests). There was a significant increase in the mean weekly tests distributed in the second wave compared to the first and third waves (p = 0.047; IC 8.29–1110.71). We found a significant difference between the weekly average of tests distributed in the first and second wave (p < 0.001; IC -209.83–76.20) to Group 2. Group 3 received the second-highest number of tests from the MoH overall, with a reduction during the third wave to first-wave levels. The distribution of RT-PCR tests was not correlated with the case and death incidence.
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spelling pubmed-104378242023-08-19 An assessment of the public health surveillance strategy based on molecular testing during three major pandemic waves of COVID-19 in Brazil Barberia, Lorena G. Boing, Alexandra Gusmão, João Miyajima, Fabio Abud, Adriano Kemp, Brigina Zamudio, Marcela Moraes de Sousa, Tatiane C. PLOS Glob Public Health Research Article A national laboratory-based surveillance system was adapted to monitor the situation of SARS-CoV-2 in Brazil. The objective of the study was to compare the challenges in implementing COVID-19 surveillance strategies based on the Ministry of Health’s (MoH) distribution of RT-PCR tests to different types of laboratories. This retrospective study analyzed the MoH’s testing policies and distribution of RT-PCR tests to laboratories during the first, second, and third waves. Recipient laboratories were divided into groups: public health laboratories that belonged to the national network of public health laboratories (Group 1); public laboratories granted authorization during the pandemic (Group 2); and High-Capacity Testing Centers (Group 3). We analyzed the timing and duration of COVID-19 testing policies and the allocation of tests to laboratories by group and wave. Using t-tests, we analyzed the difference in the weekly average of tests distributed to labs by group and using Pearson’s correlation coefficient, analyzed the test distribution according to infection and death rates. Between epiweek 9, 2020, and epiweek 22, 2022, the MoH distributed an average of 263,004 RT-PCR tests per week. The weekly average of tests distributed was highest in the second wave (310,327 tests), followed by the first (218,005 tests) and third waves (201,226 tests). There was a significant increase in the mean weekly tests distributed in the second wave compared to the first and third waves (p = 0.047; IC 8.29–1110.71). We found a significant difference between the weekly average of tests distributed in the first and second wave (p < 0.001; IC -209.83–76.20) to Group 2. Group 3 received the second-highest number of tests from the MoH overall, with a reduction during the third wave to first-wave levels. The distribution of RT-PCR tests was not correlated with the case and death incidence. Public Library of Science 2023-08-18 /pmc/articles/PMC10437824/ /pubmed/37594920 http://dx.doi.org/10.1371/journal.pgph.0002164 Text en © 2023 Barberia et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Barberia, Lorena G.
Boing, Alexandra
Gusmão, João
Miyajima, Fabio
Abud, Adriano
Kemp, Brigina
Zamudio, Marcela
Moraes de Sousa, Tatiane C.
An assessment of the public health surveillance strategy based on molecular testing during three major pandemic waves of COVID-19 in Brazil
title An assessment of the public health surveillance strategy based on molecular testing during three major pandemic waves of COVID-19 in Brazil
title_full An assessment of the public health surveillance strategy based on molecular testing during three major pandemic waves of COVID-19 in Brazil
title_fullStr An assessment of the public health surveillance strategy based on molecular testing during three major pandemic waves of COVID-19 in Brazil
title_full_unstemmed An assessment of the public health surveillance strategy based on molecular testing during three major pandemic waves of COVID-19 in Brazil
title_short An assessment of the public health surveillance strategy based on molecular testing during three major pandemic waves of COVID-19 in Brazil
title_sort assessment of the public health surveillance strategy based on molecular testing during three major pandemic waves of covid-19 in brazil
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437824/
https://www.ncbi.nlm.nih.gov/pubmed/37594920
http://dx.doi.org/10.1371/journal.pgph.0002164
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