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DNAJB3 attenuates ER stress through direct interaction with AKT

Metabolic stress involved in several dysregulation disorders such as type 2 diabetes mellitus (T2DM) results in down regulation of several heat shock proteins (HSPs) including DNAJB3. This down regulation of HSPs is associated with insulin resistance (IR) and interventions which induce the heat shoc...

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Detalles Bibliográficos
Autores principales: Islam, Zeyaul, Diane, Abdoulaye, Khattab, Namat, Dehbi, Mohammed, Thornalley, Paul, Kolatkar, Prasanna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437922/
https://www.ncbi.nlm.nih.gov/pubmed/37594932
http://dx.doi.org/10.1371/journal.pone.0290340