A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3

Animal venom peptides represent valuable compounds for biomedical exploration. The venoms of marine cone snails constitute a particularly rich source of peptide toxins, known as conotoxins. Here, we identify the sequence of an unusually large conotoxin, Mu8.1, which defines a new class of conotoxins...

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Detalles Bibliográficos
Autores principales: Hackney, Celeste M., Flórez Salcedo, Paula, Mueller, Emilie, Koch, Thomas Lund, Kjelgaard, Lau D., Watkins, Maren, Zachariassen, Linda G., Tuelung, Pernille Sønderby, McArthur, Jeffrey R., Adams, David J., Kristensen, Anders S., Olivera, Baldomero, Finol-Urdaneta, Rocio K., Safavi-Hemami, Helena, Morth, Jens Preben, Ellgaard, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437998/
https://www.ncbi.nlm.nih.gov/pubmed/37535677
http://dx.doi.org/10.1371/journal.pbio.3002217

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