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Folding stabilities of ribosome-bound nascent polypeptides probed by mass spectrometry
The folding of most proteins occurs during the course of their translation while their tRNA-bound C termini are embedded in the ribosome. How the close proximity of nascent proteins to the ribosome influences their folding thermodynamics remains poorly understood. Here, we have developed a mass spec...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438377/ https://www.ncbi.nlm.nih.gov/pubmed/37552756 http://dx.doi.org/10.1073/pnas.2303167120 |