ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways

Human cytomegalovirus (HCMV) is a major human pathogen whose life-long persistence is enabled by its remarkable capacity to systematically subvert host immune defenses. In exploring the finding that HCMV infection up-regulates tumor necrosis factor receptor 2 (TNFR2), a ligand for the pro-inflammato...

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Detalles Bibliográficos
Autores principales: Rubina, Anzelika, Patel, Mihil, Nightingale, Katie, Potts, Martin, Fielding, Ceri A., Kollnberger, Simon, Lau, Betty, Ladell, Kristin, Miners, Kelly L., Nichols, Jenna, Nobre, Luis, Roberts, Dawn, Trinca, Terrence M., Twohig, Jason P., Vlahava, Virginia-Maria, Davison, Andrew J., Price, David A., Tomasec, Peter, Wilkinson, Gavin W. G., Weekes, Michael P., Stanton, Richard J., Wang, Eddie C. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438378/
https://www.ncbi.nlm.nih.gov/pubmed/37561786
http://dx.doi.org/10.1073/pnas.2303155120

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