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Organoid cell fate dynamics in space and time

Organoids are a major new tool to study tissue renewal. However, characterizing the underlying differentiation dynamics remains challenging. Here, we developed TypeTracker, which identifies cell fates by AI-enabled cell tracking and propagating end point fates back along the branched lineage trees....

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Detalles Bibliográficos
Autores principales: Zheng, Xuan, Betjes, Max A., Ender, Pascal, Goos, Yvonne J., Huelsz-Prince, Guizela, Clevers, Hans, van Zon, Jeroen S., Tans, Sander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438469/
https://www.ncbi.nlm.nih.gov/pubmed/37595032
http://dx.doi.org/10.1126/sciadv.add6480