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XCR1 expression distinguishes human conventional dendritic cell type 1 with full effector functions from their immediate precursors

Dendritic cells (DCs) are major regulators of innate and adaptive immune responses. DCs can be classified into plasmacytoid DCs and conventional DCs (cDCs) type 1 and 2. Murine and human cDC1 share the mRNA expression of XCR1. Murine studies indicated a specific role of the XCR1–XCL1 axis in the ind...

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Detalles Bibliográficos
Autores principales: Heger, Lukas, Hatscher, Lukas, Liang, Chunguang, Lehmann, Christian H. K., Amon, Lukas, Lühr, Jennifer J., Kaszubowski, Tomasz, Nzirorera, Rayk, Schaft, Niels, Dörrie, Jan, Irrgang, Pascal, Tenbusch, Matthias, Kunz, Meik, Socher, Eileen, Autenrieth, Stella E., Purbojo, Ariawan, Sirbu, Horia, Hartmann, Arndt, Alexiou, Christoph, Cesnjevar, Robert, Dudziak, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438835/
https://www.ncbi.nlm.nih.gov/pubmed/37566635
http://dx.doi.org/10.1073/pnas.2300343120

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