Growth deregulation and interaction with host hemocytes contribute to tumor progression in a Drosophila brain tumor model

Tumors constantly interact with their microenvironment. Here, we present data on a Notch-induced neural stem cell (NSC) tumor in Drosophila, which can be immortalized by serial transplantation in adult hosts. This tumor arises in the larva by virtue of the ability of Notch to suppress early differen...

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Detalles Bibliográficos
Autores principales: Voutyraki, Chrysanthi, Choromidis, Alexandros, Meligkounaki, Anastasia, Vlachopoulos, Nikolaos Andreas, Theodorou, Vasiliki, Grammenoudi, Sofia, Athanasiadis, Emmanouil, Monticelli, Sara, Giangrande, Angela, Delidakis, Christos, Zacharioudaki, Evanthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438840/
https://www.ncbi.nlm.nih.gov/pubmed/37549261
http://dx.doi.org/10.1073/pnas.2221601120

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