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LNS8801 inhibits Acute Myeloid Leukemia by Inducing the Production of Reactive Oxygen Species and Activating the Endoplasmic Reticulum Stress Pathway

Despite recent therapeutic advances, the 5-year survival rate for adults with acute myeloid leukemia (AML) is poor and standard-of-care chemotherapy is associated with significant toxicity, highlighting the need for new therapeutic approaches. Recent work from our group and others established that t...

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Detalles Bibliográficos
Autores principales: Lee, Inyoung, Doepner, Miriam, Weissenrieder, Jillian, Majer, Ariana D., Mercado, Sophia, Estell, Angela, Natale, Christopher A., Sung, Pamela J., Foskett, J. Kevin, Carroll, Martin P., Ridky, Todd W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438922/
https://www.ncbi.nlm.nih.gov/pubmed/37599786
http://dx.doi.org/10.1158/2767-9764.CRC-22-0478