Cargando…

Gentiopicroside modulates glucose homeostasis in high-fat-diet and streptozotocin-induced type 2 diabetic mice

Gluconeogenesis is closely related to the occurrence and development of type 2 diabetes mellitus (T2DM). Gentiopicroside (GPS) is the main active secoiridoid glycoside in Gentiana manshurica Kitagawa, which can improve chronic complications associated with diabetes and regulate glucose metabolism. H...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xing, Long, Dongmei, Hu, Xianghong, Guo, Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10438990/ https://www.ncbi.nlm.nih.gov/pubmed/37601073 http://dx.doi.org/10.3389/fphar.2023.1172360

Ejemplares similares

Gentiopicroside improves high-fat diet-induced NAFLD in association with modulation of host serum metabolome and gut microbiome in mice
por: Wang, Lijuan, et al.
Publicado: (2023)

Gallic Acid Ameliorated Impaired Lipid Homeostasis in a Mouse Model of High-Fat Diet—and Streptozotocin-Induced NAFLD and Diabetes through Improvement of β-oxidation and Ketogenesis
por: Chao, Jung, et al.
Publicado: (2021)

Gentiopicroside Ameliorates Diabetic Renal Tubulointerstitial Fibrosis via Inhibiting the AT1R/CK2/NF-κB Pathway
por: Xu, Zhanchi, et al.
Publicado: (2022)

Bu-Shen-Huo-Xue Decoction Ameliorates Diabetic Nephropathy by Inhibiting Rac1/PAK1/p38MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Mice
por: Wang, Weisong, et al.
Publicado: (2020)

Comparative Evaluation of the Effect of Metformin and Insulin on Gut Microbiota and Metabolome Profiles of Type 2 Diabetic Rats Induced by the Combination of Streptozotocin and High-Fat Diet
por: Hu, Nan, et al.
Publicado: (2022)

Antidiabetic and Antilipidemic Effect of Musa balbisiana Root Extract: A Potent Agent for Glucose Homeostasis in Streptozotocin-Induced Diabetic Rat
por: Kalita, Himadri, et al.
Publicado: (2016)

Preventive and Therapeutic Effects of Astaxanthin on Depressive-Like Behaviors in High-Fat Diet and Streptozotocin-Treated Rats
por: Ke, Yuting, et al.
Publicado: (2020)

Protective effect of heat-processed Gynostemma pentaphyllum on high fat diet-induced glucose metabolic disorders mice
por: Xie, Jin-Bo, et al.
Publicado: (2023)

Isorhamnetin Reduces Glucose Level, Inflammation, and Oxidative Stress in High-Fat Diet/Streptozotocin Diabetic Mice Model
por: Alqudah, Abdelrahim, et al.
Publicado: (2023)

Antidiabetic activity of Berberis brandisiana is possibly mediated through modulation of insulin signaling pathway, inflammatory cytokines and adipocytokines in high fat diet and streptozotocin-administered rats
por: Mehdi, Shumaila, et al.
Publicado: (2023)

Effect of Berberine on Atherosclerosis and Gut Microbiota Modulation and Their Correlation in High-Fat Diet-Fed ApoE−/− Mice
por: Wu, Min, et al.
Publicado: (2020)

Polydextrose Alleviates Adipose Tissue Inflammation and Modulates the Gut Microbiota in High-Fat Diet-Fed Mice
por: Hu, Qiuyue, et al.
Publicado: (2022)

Protopanaxadiol and Protopanaxatriol-Type Saponins Ameliorate Glucose and Lipid Metabolism in Type 2 Diabetes Mellitus in High-Fat Diet/Streptozocin-Induced Mice
por: Deng, Jianjun, et al.
Publicado: (2017)

Renal Protective Effects of Inonotus obliquus on High-Fat Diet/Streptozotocin-Induced Diabetic Kidney Disease Rats: Biochemical, Color Doppler Ultrasound and Histopathological Evidence
por: Zhang, Yan, et al.
Publicado: (2022)

Myricitrin Ameliorates Hyperglycemia, Glucose Intolerance, Hepatic Steatosis, and Inflammation in High-Fat Diet/Streptozotocin-Induced Diabetic Mice
por: Kim, Do Yeon, et al.
Publicado: (2020)

Water Extract of Potentilla discolor Bunge Improves Hepatic Glucose Homeostasis by Regulating Gluconeogenesis and Glycogen Synthesis in High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Mice
por: Li, Tiange, et al.
Publicado: (2020)

Effects of High-Fat and High-Fat/High-Sucrose Diet-Induced Obesity on PVAT Modulation of Vascular Function in Male and Female Mice
por: Victorio, Jamaira A., et al.
Publicado: (2021)

Effects of Gentiopicroside on activation of NLRP3 inflammasome in acute gouty arthritis mice induced by MSU
por: He, Menglin, et al.
Publicado: (2021)

Nerium oleander Distillate Improves Fat and Glucose Metabolism in High-Fat Diet-Fed Streptozotocin-Induced Diabetic Rats
por: Bas, Ahmet Levent, et al.
Publicado: (2012)

Anti-Rheumatic Properties of Gentiopicroside Are Associated With Suppression of ROS-NF-κB-NLRP3 Axis in Fibroblast-Like Synoviocytes and NF-κB Pathway in Adjuvant-Induced Arthritis
por: Wang, Meiling, et al.
Publicado: (2020)

Exogenous Pancreatic Kallikrein Improves Diabetic Cardiomyopathy in Streptozotocin-Induced Diabetes
por: Wu, Meng, et al.
Publicado: (2018)

Potential benefits of metformin and pioglitazone combination therapy via gut microbiota and metabolites in high-fat diet-fed mice
por: Wang, Dongmei, et al.
Publicado: (2022)

Gentiopicroside Ameliorates the Progression from Hepatic Steatosis to Fibrosis Induced by Chronic Alcohol Intake
por: Yang, Hong-Xu, et al.
Publicado: (2020)

High-Fat Diet Alters the Intestinal Microbiota in Streptozotocin-Induced Type 2 Diabetic Mice
por: Liu, Sheng, et al.
Publicado: (2019)

Gossypol from Cottonseeds Ameliorates Glucose Uptake by Mimicking Insulin Signaling and Improves Glucose Homeostasis in Mice with Streptozotocin-Induced Diabetes
por: Alam, Md Badrul, et al.
Publicado: (2018)

The Protective Effects of Sulforaphane on High-Fat Diet-Induced Obesity in Mice Through Browning of White Fat
por: Liu, Yaoli, et al.
Publicado: (2021)

The Effect of Simvastatin on Glucose Homeostasis in Streptozotocin Induced Type 2 Diabetic Rats
por: Wang, Lulu, et al.
Publicado: (2013)

Usnea improves high-fat diet- and vitamin D3-induced atherosclerosis in rats by remodeling intestinal flora homeostasis
por: Liu, Yanjun, et al.
Publicado: (2022)

Crocin-I Protects Against High-Fat Diet-Induced Obesity via Modulation of Gut Microbiota and Intestinal Inflammation in Mice
por: Xie, Xiaoxian, et al.
Publicado: (2022)

Butyrate Improves the Metabolic Disorder and Gut Microbiome Dysbiosis in Mice Induced by a High-Fat Diet
por: Gao, Feng, et al.
Publicado: (2019)

Resveratrol Attenuates High-Fat Diet Induced Hepatic Lipid Homeostasis Disorder and Decreases m(6)A RNA Methylation
por: Wu, Jiamin, et al.
Publicado: (2020)

PPARγ Transcription Deficiency Exacerbates High-Fat Diet-Induced Adipocyte Hypertrophy and Insulin Resistance in Mice
por: Guo, Fusheng, et al.
Publicado: (2020)

Effects of the fenugreek extracts on high‐fat diet‐fed and streptozotocin‐induced type 2 diabetic mice
por: Li, Xiao‐yan, et al.
Publicado: (2018)

Impaired Lipid and Glucose Homeostasis in Hexabromocyclododecane-Exposed Mice Fed a High-Fat Diet
por: Yanagisawa, Rie, et al.
Publicado: (2014)

Metabolomics Reveals Effect of Zishen Jiangtang Pill, a Chinese Herbal Product on High-Fat Diet-Induced Type 2 Diabetes Mellitus in Mice
por: Chen, Jianping, et al.
Publicado: (2019)

Characterization of Mechanical Allodynia and Skin Innervation in a Mouse Model of Type-2 Diabetes Induced by Cafeteria-Style Diet and Low-Doses of Streptozotocin
por: Castañeda-Corral, Gabriela, et al.
Publicado: (2021)

Anti-Diabetic Effects of Ethanol Extract from Sanghuangporous vaninii in High-Fat/Sucrose Diet and Streptozotocin-Induced Diabetic Mice by Modulating Gut Microbiota
por: Huang, Zi-Rui, et al.
Publicado: (2022)

Gentiopicroside-Loaded Chitosan Nanoparticles Inhibit TNF-α-Induced Proliferation and Inflammatory Response in HaCaT Keratinocytes and Ameliorate Imiquimod-Induced Dermatitis Lesions in Mice
por: Zhao, Kaixuan, et al.
Publicado: (2023)

CTRP1 prevents high fat diet-induced obesity and improves glucose homeostasis in obese and STZ-induced diabetic mice
por: Ren, Mingzhi, et al.
Publicado: (2022)

Cooperative Anti-Diabetic Effects of Deoxynojirimycin-Polysaccharide by Inhibiting Glucose Absorption and Modulating Glucose Metabolism in Streptozotocin-Induced Diabetic Mice
por: Li, You-Gui, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_acbtapo25kcc0ld1n9k6ev44vl