SGLT5 is the renal transporter for 1,5-anhydroglucitol, a major player in two rare forms of neutropenia

Neutropenia and neutrophil dysfunction in glycogen storage disease type 1b (GSD1b) and severe congenital neutropenia type 4 (SCN4), associated with deficiencies of the glucose-6-phosphate transporter (G6PT/SLC37A4) and the phosphatase G6PC3, respectively, are the result of the accumulation of 1,5-an...

Descripción completa

Detalles Bibliográficos
Autores principales: Diederich, Jennifer, Mounkoro, Pierre, Tirado, Hernan A., Chevalier, Nathalie, Van Schaftingen, Emile, Veiga-da-Cunha, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439028/
https://www.ncbi.nlm.nih.gov/pubmed/37594549
http://dx.doi.org/10.1007/s00018-023-04884-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439028/
https://www.ncbi.nlm.nih.gov/pubmed/37594549
http://dx.doi.org/10.1007/s00018-023-04884-8

Ejemplares similares