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Sodium bicarbonate as a local adjunctive agent for limiting platelet activation, aggregation, and adhesion within cardiovascular therapeutic devices

Cardiovascular therapeutic devices (CTDs) remain limited by thrombotic adverse events. Current antithrombotic agents limit thrombosis partially, often adding to bleeding. The Impella® blood pump utilizes heparin in 5% dextrose (D5W) as an internal purge to limit thrombosis. While effective, exogenou...

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Detalles Bibliográficos
Autores principales: Ammann, Kaitlyn R., Outridge, Christine E., Roka-Moiia, Yana, Muslmani, Sami, Ding, Jun, Italiano, Joseph E., Tomat, Elisa, Corbett, Scott, Slepian, Marvin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439054/
https://www.ncbi.nlm.nih.gov/pubmed/37432612
http://dx.doi.org/10.1007/s11239-023-02852-4