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Bioavailability of Melatonin after Administration of an Oral Prolonged-Release Tablet and an Immediate-Release Sublingual Spray in Healthy Male Volunteers
BACKGROUND: The benefit of exogenous melatonin is based on its bioavailability, which depends on the galenic form, the route of administration, the dosage, and the individual absorption and rate of hepatic metabolism. OBJECTIVE: The objective of this study is to investigate the bioavailability of me...
Autores principales: | Ait Abdellah, Samira, Raverot, Véronique, Gal, Caroline, Guinobert, Isabelle, Bardot, Valérie, Blondeau, Claude, Claustrat, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439092/ https://www.ncbi.nlm.nih.gov/pubmed/37438493 http://dx.doi.org/10.1007/s40268-023-00431-9 |
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