Strategic considerations on developing a CHIKV vaccine and ensuring equitable access for countries in need

Chikungunya is an arboviral disease caused by the chikungunya virus (CHIKV) afflicting tropical and sub-tropical countries worldwide. It has been identified as a priority pathogen by the Coalition for Epidemics Preparedness Innovations (CEPI) and as an emerging infectious disease (EID) necessitating...

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Autores principales: Cherian, Neil, Bettis, Alison, Deol, Arminder, Kumar, Arun, Di Fabio, Jose Luis, Chaudhari, Amol, Yimer, Solomon, Fahim, Raafat, Endy, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439111/
https://www.ncbi.nlm.nih.gov/pubmed/37596253
http://dx.doi.org/10.1038/s41541-023-00722-x
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author Cherian, Neil
Bettis, Alison
Deol, Arminder
Kumar, Arun
Di Fabio, Jose Luis
Chaudhari, Amol
Yimer, Solomon
Fahim, Raafat
Endy, Timothy
author_facet Cherian, Neil
Bettis, Alison
Deol, Arminder
Kumar, Arun
Di Fabio, Jose Luis
Chaudhari, Amol
Yimer, Solomon
Fahim, Raafat
Endy, Timothy
author_sort Cherian, Neil
collection PubMed
description Chikungunya is an arboviral disease caused by the chikungunya virus (CHIKV) afflicting tropical and sub-tropical countries worldwide. It has been identified as a priority pathogen by the Coalition for Epidemics Preparedness Innovations (CEPI) and as an emerging infectious disease (EID) necessitating further action as soon as possible by the World Health Organization (WHO). Recent studies suggest that disability-adjusted life years (DALYs) due to CHIKV infection are as high as 106,089 DALYs lost globally. Significant progress has been made in the development of several vaccines, aimed at preventing CHIKV infections. This perspective article summarizes CEPI’s efforts and strategic considerations for developing a CHIKV vaccine and ensuring equitable access for CHIKV endemic countries.
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spelling pubmed-104391112023-08-20 Strategic considerations on developing a CHIKV vaccine and ensuring equitable access for countries in need Cherian, Neil Bettis, Alison Deol, Arminder Kumar, Arun Di Fabio, Jose Luis Chaudhari, Amol Yimer, Solomon Fahim, Raafat Endy, Timothy NPJ Vaccines Perspective Chikungunya is an arboviral disease caused by the chikungunya virus (CHIKV) afflicting tropical and sub-tropical countries worldwide. It has been identified as a priority pathogen by the Coalition for Epidemics Preparedness Innovations (CEPI) and as an emerging infectious disease (EID) necessitating further action as soon as possible by the World Health Organization (WHO). Recent studies suggest that disability-adjusted life years (DALYs) due to CHIKV infection are as high as 106,089 DALYs lost globally. Significant progress has been made in the development of several vaccines, aimed at preventing CHIKV infections. This perspective article summarizes CEPI’s efforts and strategic considerations for developing a CHIKV vaccine and ensuring equitable access for CHIKV endemic countries. Nature Publishing Group UK 2023-08-18 /pmc/articles/PMC10439111/ /pubmed/37596253 http://dx.doi.org/10.1038/s41541-023-00722-x Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Perspective
Cherian, Neil
Bettis, Alison
Deol, Arminder
Kumar, Arun
Di Fabio, Jose Luis
Chaudhari, Amol
Yimer, Solomon
Fahim, Raafat
Endy, Timothy
Strategic considerations on developing a CHIKV vaccine and ensuring equitable access for countries in need
title Strategic considerations on developing a CHIKV vaccine and ensuring equitable access for countries in need
title_full Strategic considerations on developing a CHIKV vaccine and ensuring equitable access for countries in need
title_fullStr Strategic considerations on developing a CHIKV vaccine and ensuring equitable access for countries in need
title_full_unstemmed Strategic considerations on developing a CHIKV vaccine and ensuring equitable access for countries in need
title_short Strategic considerations on developing a CHIKV vaccine and ensuring equitable access for countries in need
title_sort strategic considerations on developing a chikv vaccine and ensuring equitable access for countries in need
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439111/
https://www.ncbi.nlm.nih.gov/pubmed/37596253
http://dx.doi.org/10.1038/s41541-023-00722-x
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