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A potent and durable malaria transmission-blocking vaccine designed from a single-component 60-copy Pfs230D1 nanoparticle

Malaria transmission-blocking vaccines (TBVs) reduce disease transmission by breaking the continuous cycle of infection between the human host and the mosquito vector. Domain 1 (D1) of Pfs230 is a leading TBV candidate and comprises the majority of transmission-reducing activity (TRA) elicited by Pf...

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Detalles Bibliográficos
Autores principales: Salinas, Nichole D., Ma, Rui, Dickey, Thayne H., McAleese, Holly, Ouahes, Tarik, Long, Carole A., Miura, Kazutoyo, Lambert, Lynn E., Tolia, Niraj H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439124/
https://www.ncbi.nlm.nih.gov/pubmed/37596283
http://dx.doi.org/10.1038/s41541-023-00709-8