Cargando…
A potent and durable malaria transmission-blocking vaccine designed from a single-component 60-copy Pfs230D1 nanoparticle
Malaria transmission-blocking vaccines (TBVs) reduce disease transmission by breaking the continuous cycle of infection between the human host and the mosquito vector. Domain 1 (D1) of Pfs230 is a leading TBV candidate and comprises the majority of transmission-reducing activity (TRA) elicited by Pf...
Autores principales: | Salinas, Nichole D., Ma, Rui, Dickey, Thayne H., McAleese, Holly, Ouahes, Tarik, Long, Carole A., Miura, Kazutoyo, Lambert, Lynn E., Tolia, Niraj H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439124/ https://www.ncbi.nlm.nih.gov/pubmed/37596283 http://dx.doi.org/10.1038/s41541-023-00709-8 |
Ejemplares similares
-
Structure-based design of a strain transcending AMA1-RON2L malaria vaccine
por: Patel, Palak N., et al.
Publicado: (2023) -
Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine
por: Dickey, Thayne H., et al.
Publicado: (2023) -
Design of the SARS-CoV-2 RBD vaccine antigen improves neutralizing antibody response
por: Dickey, Thayne H., et al.
Publicado: (2022) -
Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines
por: Dickey, Thayne H., et al.
Publicado: (2023) -
Particle-based, Pfs230 and Pfs25 immunization is effective, but not improved by duplexing at fixed total antigen dose
por: Huang, Wei-Chiao, et al.
Publicado: (2020)