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An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver
A perimetastatic capsule is a strong positive prognostic factor in liver metastases, but its origin remains unclear. Here, we systematically quantify the capsule’s extent and cellular composition in 263 patients with colorectal cancer liver metastases to investigate its clinical significance and ori...
Autores principales: | Fernández Moro, Carlos, Geyer, Natalie, Harrizi, Sara, Hamidi, Yousra, Söderqvist, Sara, Kuznyecov, Danyil, Tidholm Qvist, Evelina, Salmonson Schaad, Media, Hermann, Laura, Lindberg, Amanda, Heuchel, Rainer L., Martín-Bernabé, Alfonso, Dhanjal, Soniya, Navis, Anna C., Villard, Christina, del Valle, Andrea C., Bozóky, Lorand, Sparrelid, Ernesto, Dirix, Luc, Strell, Carina, Östman, Arne, Schmierer, Bernhard, Vermeulen, Peter B., Engstrand, Jennie, Bozóky, Béla, Gerling, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439160/ https://www.ncbi.nlm.nih.gov/pubmed/37596278 http://dx.doi.org/10.1038/s41467-023-40688-x |
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