Picolinic acid is a broad-spectrum inhibitor of enveloped virus entry that restricts SARS-CoV-2 and influenza A virus in vivo

The COVID-19 pandemic highlights an urgent need for effective antivirals. Targeting host processes co-opted by viruses is an attractive antiviral strategy with a high resistance barrier. Picolinic acid (PA) is a tryptophan metabolite endogenously produced in mammals. Here, we report the broad-spectr...

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Detalles Bibliográficos
Autores principales: Narayan, Rohan, Sharma, Mansi, Yadav, Rajesh, Biji, Abhijith, Khatun, Oyahida, Kaur, Sumandeep, Kanojia, Aditi, Joy, Christy Margrat, Rajmani, Raju, Sharma, Pallavi Raj, Jeyasankar, Sharumathi, Rani, Priya, Shandil, Radha Krishan, Narayanan, Shridhar, Rao, Durga Chilakalapudi, Satchidanandam, Vijaya, Das, Saumitra, Agarwal, Rachit, Tripathi, Shashank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439173/
https://www.ncbi.nlm.nih.gov/pubmed/37463584
http://dx.doi.org/10.1016/j.xcrm.2023.101127

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