Cargando…
Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
The combination of endocrine therapy (ET) and cyclin-dependent kinase 4/6 (CDK4/6) inhibitors (CDK4/6i) was a hallmark in metastatic luminal breast cancer (BC). However, intrinsic and acquired resistance affects long-term efficacy. Here, we study the role of the receptor activator of nuclear factor-...
Autores principales: | Gomes, Inês, Gallego-Paez, Lina M., Jiménez, Maria, Santamaria, Patricia G., Mansinho, André, Sousa, Rita, Abreu, Catarina, Suárez, Eva González, Costa, Luis, Casimiro, Sandra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439176/ https://www.ncbi.nlm.nih.gov/pubmed/37451269 http://dx.doi.org/10.1016/j.xcrm.2023.101120 |
Ejemplares similares
-
The prognostic role of RANK SNP rs34945627 in breast cancer patients with bone metastases
por: Ferreira, Arlindo, et al.
Publicado: (2016) -
The Evolving Pathways of the Efficacy of and Resistance to CDK4/6 Inhibitors in Breast Cancer
por: Gomes, Inês, et al.
Publicado: (2023) -
The Roadmap of RANKL/RANK Pathway in Cancer
por: Casimiro, Sandra, et al.
Publicado: (2021) -
Luminal Rank loss decreases cell fitness leading to basal cell bipotency in parous mammary glands
por: Rocha, Ana Sofia, et al.
Publicado: (2023) -
Levels of Circulating Fibroblast Growth Factor 23 (FGF23) and Prognosis in Cancer Patients with Bone Metastases
por: Mansinho, André, et al.
Publicado: (2019)