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Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired
Mitochondrial quality control is critical for cardiac homeostasis as these organelles are responsible for generating most of the energy needed to sustain contraction. Dysfunctional mitochondria are normally degraded via intracellular degradation pathways that converge on the lysosome. Here, we ident...
Autores principales: | Liang, Wenjing, Sagar, Shakti, Ravindran, Rishith, Najor, Rita H., Quiles, Justin M., Chi, Liguo, Diao, Rachel Y., Woodall, Benjamin P., Leon, Leonardo J., Zumaya, Erika, Duran, Jason, Cauvi, David M., De Maio, Antonio, Adler, Eric D., Gustafsson, Åsa B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439183/ https://www.ncbi.nlm.nih.gov/pubmed/37596294 http://dx.doi.org/10.1038/s41467-023-40680-5 |
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