Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing

Moderate inflammation is essential for standard wound healing. In pathological conditions, such as diabetes, protracted and refractory wounds are associated with excessive inflammation, manifested by persistent proinflammatory macrophage states. However, the mechanisms are still unclear. Herein, we...

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Detalles Bibliográficos
Autores principales: Lv, Dongming, Cao, Xiaoling, Zhong, Li, Dong, Yunxian, Xu, Zhongye, Rong, Yanchao, Xu, Hailin, Wang, Zhiyong, Yang, Hao, Yin, Rong, Chen, Miao, Ke, Chao, Hu, Zhicheng, Deng, Wuguo, Tang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439185/
https://www.ncbi.nlm.nih.gov/pubmed/37480849
http://dx.doi.org/10.1016/j.xcrm.2023.101129

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