Cargando…
An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases
Signal regulatory protein (SIRPα) is an immune inhibitory receptor expressed by myeloid cells to inhibit immune cell phagocytosis, migration, and activation. Despite the progress of SIRPα and CD47 antagonist antibodies to promote anti-cancer immunity, it is not yet known whether SIRPα receptor agoni...
Autores principales: | Xie, Markus M., Dai, Bingbing, Hackney, Jason A., Sun, Tianhe, Zhang, Juan, Jackman, Janet K., Jeet, Surinder, Irizarry-Caro, Ricardo A., Fu, Yongyao, Liang, Yuxin, Bender, Hannah, Shamir, Eliah R., Keir, Mary E., Bevers, Jack, Nakamura, Gerald, Townsend, Michael J., Fox, David A., Scherl, Alexis, Lee, Wyne P., Martin, Flavius, Godowski, Paul J., Pappu, Rajita, Yi, Tangsheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439247/ https://www.ncbi.nlm.nih.gov/pubmed/37490914 http://dx.doi.org/10.1016/j.xcrm.2023.101130 |
Ejemplares similares
-
Obligate role for Rock1 and Rock2 in adult stem cell viability and function
por: Sambandam, Arivazhagan, et al.
Publicado: (2023) -
Dual targeting of lymphocyte homing and retention through α4β7 and αEβ7 inhibition in inflammatory bowel disease
por: Dai, Bingbing, et al.
Publicado: (2021) -
The role of IL-22 in intestinal health and disease
por: Keir, Mary E., et al.
Publicado: (2020) -
Myoepithelial cells are a dynamic barrier to epithelial dissemination
por: Sirka, Orit Katarina, et al.
Publicado: (2018) -
Epstein-Barr Virus Latent Membrane Protein 2a (Lmp2a) Employs the Slp-65 Signaling Module
por: Engels, Niklas, et al.
Publicado: (2001)