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An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases

Signal regulatory protein (SIRPα) is an immune inhibitory receptor expressed by myeloid cells to inhibit immune cell phagocytosis, migration, and activation. Despite the progress of SIRPα and CD47 antagonist antibodies to promote anti-cancer immunity, it is not yet known whether SIRPα receptor agoni...

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Detalles Bibliográficos
Autores principales: Xie, Markus M., Dai, Bingbing, Hackney, Jason A., Sun, Tianhe, Zhang, Juan, Jackman, Janet K., Jeet, Surinder, Irizarry-Caro, Ricardo A., Fu, Yongyao, Liang, Yuxin, Bender, Hannah, Shamir, Eliah R., Keir, Mary E., Bevers, Jack, Nakamura, Gerald, Townsend, Michael J., Fox, David A., Scherl, Alexis, Lee, Wyne P., Martin, Flavius, Godowski, Paul J., Pappu, Rajita, Yi, Tangsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439247/
https://www.ncbi.nlm.nih.gov/pubmed/37490914
http://dx.doi.org/10.1016/j.xcrm.2023.101130

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