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RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease

Digital health data used in diagnostics, patient care, and oncology research continue to accumulate exponentially. Most medical information, and particularly radiology results, are stored in free-text format, and the potential of these data remains untapped. In this study, a radiological repomics-dr...

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Autores principales: Zhang, Tianyu, Tan, Tao, Wang, Xin, Gao, Yuan, Han, Luyi, Balkenende, Luuk, D’Angelo, Anna, Bao, Lingyun, Horlings, Hugo M., Teuwen, Jonas, Beets-Tan, Regina G.H., Mann, Ritse M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439251/
https://www.ncbi.nlm.nih.gov/pubmed/37490915
http://dx.doi.org/10.1016/j.xcrm.2023.101131
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author Zhang, Tianyu
Tan, Tao
Wang, Xin
Gao, Yuan
Han, Luyi
Balkenende, Luuk
D’Angelo, Anna
Bao, Lingyun
Horlings, Hugo M.
Teuwen, Jonas
Beets-Tan, Regina G.H.
Mann, Ritse M.
author_facet Zhang, Tianyu
Tan, Tao
Wang, Xin
Gao, Yuan
Han, Luyi
Balkenende, Luuk
D’Angelo, Anna
Bao, Lingyun
Horlings, Hugo M.
Teuwen, Jonas
Beets-Tan, Regina G.H.
Mann, Ritse M.
author_sort Zhang, Tianyu
collection PubMed
description Digital health data used in diagnostics, patient care, and oncology research continue to accumulate exponentially. Most medical information, and particularly radiology results, are stored in free-text format, and the potential of these data remains untapped. In this study, a radiological repomics-driven model incorporating medical token cognition (RadioLOGIC) is proposed to extract repomics (report omics) features from unstructured electronic health records and to assess human health and predict pathological outcome via transfer learning. The average accuracy and F1-weighted score for the extraction of repomics features using RadioLOGIC are 0.934 and 0.934, respectively, and 0.906 and 0.903 for the prediction of breast imaging-reporting and data system scores. The areas under the receiver operating characteristic curve for the prediction of pathological outcome without and with transfer learning are 0.912 and 0.945, respectively. RadioLOGIC outperforms cohort models in the capability to extract features and also reveals promise for checking clinical diagnoses directly from electronic health records.
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spelling pubmed-104392512023-08-20 RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease Zhang, Tianyu Tan, Tao Wang, Xin Gao, Yuan Han, Luyi Balkenende, Luuk D’Angelo, Anna Bao, Lingyun Horlings, Hugo M. Teuwen, Jonas Beets-Tan, Regina G.H. Mann, Ritse M. Cell Rep Med Article Digital health data used in diagnostics, patient care, and oncology research continue to accumulate exponentially. Most medical information, and particularly radiology results, are stored in free-text format, and the potential of these data remains untapped. In this study, a radiological repomics-driven model incorporating medical token cognition (RadioLOGIC) is proposed to extract repomics (report omics) features from unstructured electronic health records and to assess human health and predict pathological outcome via transfer learning. The average accuracy and F1-weighted score for the extraction of repomics features using RadioLOGIC are 0.934 and 0.934, respectively, and 0.906 and 0.903 for the prediction of breast imaging-reporting and data system scores. The areas under the receiver operating characteristic curve for the prediction of pathological outcome without and with transfer learning are 0.912 and 0.945, respectively. RadioLOGIC outperforms cohort models in the capability to extract features and also reveals promise for checking clinical diagnoses directly from electronic health records. Elsevier 2023-07-24 /pmc/articles/PMC10439251/ /pubmed/37490915 http://dx.doi.org/10.1016/j.xcrm.2023.101131 Text en © 2023 The Authors. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Zhang, Tianyu
Tan, Tao
Wang, Xin
Gao, Yuan
Han, Luyi
Balkenende, Luuk
D’Angelo, Anna
Bao, Lingyun
Horlings, Hugo M.
Teuwen, Jonas
Beets-Tan, Regina G.H.
Mann, Ritse M.
RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease
title RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease
title_full RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease
title_fullStr RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease
title_full_unstemmed RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease
title_short RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease
title_sort radiologic, a healthcare model for processing electronic health records and decision-making in breast disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439251/
https://www.ncbi.nlm.nih.gov/pubmed/37490915
http://dx.doi.org/10.1016/j.xcrm.2023.101131
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