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RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease
Digital health data used in diagnostics, patient care, and oncology research continue to accumulate exponentially. Most medical information, and particularly radiology results, are stored in free-text format, and the potential of these data remains untapped. In this study, a radiological repomics-dr...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439251/ https://www.ncbi.nlm.nih.gov/pubmed/37490915 http://dx.doi.org/10.1016/j.xcrm.2023.101131 |
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author | Zhang, Tianyu Tan, Tao Wang, Xin Gao, Yuan Han, Luyi Balkenende, Luuk D’Angelo, Anna Bao, Lingyun Horlings, Hugo M. Teuwen, Jonas Beets-Tan, Regina G.H. Mann, Ritse M. |
author_facet | Zhang, Tianyu Tan, Tao Wang, Xin Gao, Yuan Han, Luyi Balkenende, Luuk D’Angelo, Anna Bao, Lingyun Horlings, Hugo M. Teuwen, Jonas Beets-Tan, Regina G.H. Mann, Ritse M. |
author_sort | Zhang, Tianyu |
collection | PubMed |
description | Digital health data used in diagnostics, patient care, and oncology research continue to accumulate exponentially. Most medical information, and particularly radiology results, are stored in free-text format, and the potential of these data remains untapped. In this study, a radiological repomics-driven model incorporating medical token cognition (RadioLOGIC) is proposed to extract repomics (report omics) features from unstructured electronic health records and to assess human health and predict pathological outcome via transfer learning. The average accuracy and F1-weighted score for the extraction of repomics features using RadioLOGIC are 0.934 and 0.934, respectively, and 0.906 and 0.903 for the prediction of breast imaging-reporting and data system scores. The areas under the receiver operating characteristic curve for the prediction of pathological outcome without and with transfer learning are 0.912 and 0.945, respectively. RadioLOGIC outperforms cohort models in the capability to extract features and also reveals promise for checking clinical diagnoses directly from electronic health records. |
format | Online Article Text |
id | pubmed-10439251 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-104392512023-08-20 RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease Zhang, Tianyu Tan, Tao Wang, Xin Gao, Yuan Han, Luyi Balkenende, Luuk D’Angelo, Anna Bao, Lingyun Horlings, Hugo M. Teuwen, Jonas Beets-Tan, Regina G.H. Mann, Ritse M. Cell Rep Med Article Digital health data used in diagnostics, patient care, and oncology research continue to accumulate exponentially. Most medical information, and particularly radiology results, are stored in free-text format, and the potential of these data remains untapped. In this study, a radiological repomics-driven model incorporating medical token cognition (RadioLOGIC) is proposed to extract repomics (report omics) features from unstructured electronic health records and to assess human health and predict pathological outcome via transfer learning. The average accuracy and F1-weighted score for the extraction of repomics features using RadioLOGIC are 0.934 and 0.934, respectively, and 0.906 and 0.903 for the prediction of breast imaging-reporting and data system scores. The areas under the receiver operating characteristic curve for the prediction of pathological outcome without and with transfer learning are 0.912 and 0.945, respectively. RadioLOGIC outperforms cohort models in the capability to extract features and also reveals promise for checking clinical diagnoses directly from electronic health records. Elsevier 2023-07-24 /pmc/articles/PMC10439251/ /pubmed/37490915 http://dx.doi.org/10.1016/j.xcrm.2023.101131 Text en © 2023 The Authors. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Zhang, Tianyu Tan, Tao Wang, Xin Gao, Yuan Han, Luyi Balkenende, Luuk D’Angelo, Anna Bao, Lingyun Horlings, Hugo M. Teuwen, Jonas Beets-Tan, Regina G.H. Mann, Ritse M. RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease |
title | RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease |
title_full | RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease |
title_fullStr | RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease |
title_full_unstemmed | RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease |
title_short | RadioLOGIC, a healthcare model for processing electronic health records and decision-making in breast disease |
title_sort | radiologic, a healthcare model for processing electronic health records and decision-making in breast disease |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439251/ https://www.ncbi.nlm.nih.gov/pubmed/37490915 http://dx.doi.org/10.1016/j.xcrm.2023.101131 |
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