Cargando…

mRNA vaccination boosts S-specific T cell memory and promotes expansion of CD45RA(int) T(EMRA)-like CD8(+) T cells in COVID-19 recovered individuals

SARS-CoV-2 infection and mRNA vaccination both elicit spike (S)-specific T cell responses. To analyze how T cell memory from prior infection influences T cell responses to vaccination, we evaluated functional T cell responses in naive and previously infected vaccine recipients. Pre-vaccine S-specifi...

Descripción completa

Detalles Bibliográficos
Autores principales: Mayer-Blackwell, Koshlan, Ryu, Heeju, Codd, Amy S., Parks, K. Rachael, MacMillan, Hugh R., Cohen, Kristen W., Stewart, Terri L., Seese, Aaron, Lemos, Maria P., De Rosa, Stephen C., Czartoski, Julie L., Moodie, Zoe, Nguyen, Long T., McGuire, Donald J., Ahmed, Rafi, Fiore-Gartland, Andrew, McElrath, M. Juliana, Newell, Evan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439252/
https://www.ncbi.nlm.nih.gov/pubmed/37552991
http://dx.doi.org/10.1016/j.xcrm.2023.101149