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METTL3 drives NAFLD-related hepatocellular carcinoma and is a therapeutic target for boosting immunotherapy

Non-alcoholic fatty liver disease (NAFLD) is an emerging risk factor of hepatocellular carcinoma (HCC). However, the mechanism and target therapy of NAFLD-HCC are still unclear. Here, we identify that the N(6)-methyladenosine (m(6)A) methyltransferase METTL3 promotes NAFLD-HCC. Hepatocyte-specific M...

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Detalles Bibliográficos
Autores principales:	Pan, Yasi, Chen, Huarong, Zhang, Xiang, Liu, Weixin, Ding, Yanqiang, Huang, Dan, Zhai, Jianning, Wei, Wenchao, Wen, Jun, Chen, Danyu, Zhou, Yunfei, Liang, Cong, Wong, Nathalie, Man, Kwan, Cheung, Alvin Ho-Kwan, Wong, Chi Chun, Yu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439254/ https://www.ncbi.nlm.nih.gov/pubmed/37586322 http://dx.doi.org/10.1016/j.xcrm.2023.101144

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